Effective and functional connectivity patterns during contextual fear conditioning

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Behavioral and autonomic dynamics during contextual fear conditioning in mice.

Aversive conditioning to contextual stimulation was performed in mice implanted with ECG transmitters to investigate heart rate (HR) and behavioral responses during contextual retention. The dynamics of HR were analyzed by advanced nonlinear techniques to uncover central neuroautonomic outflow inferred from its sympathetic (SNS) and parasympathetic (PNS) projection onto the sinus node of the he...

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Contextual fear conditioning in zebrafish.

Zebrafish are a genetically tractable vertebrate that hold considerable promise for elucidating the molecular basis of behavior. Although numerous recent advances have been made in the ability to precisely manipulate the zebrafish genome, much less is known about many aspects of learning and memory in adult fish. Here, we describe the development of a contextual fear conditioning paradigm using...

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Spectral characteristics of the hippocampal LFP during contextual fear conditioning.

OBJECTIVE The hippocampus has an important role in the acquisition and recall of aversive memories. The objective of this study was to investigate the relationship among hippocampal rhythms. METHODS Microeletrodes arrays were implanted in the hippocampus of Wistar rats. The animals were trained and tested in a contextual fear conditioning task. The training consisted in applying shocks in the...

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Estrogen modulates sexually dimorphic contextual fear conditioning

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Prefrontal neuronal circuits of contextual fear conditioning.

Over the past years, numerous studies have provided a clear understanding of the neuronal circuits and mechanisms involved in the formation, expression and extinction phases of conditioned cued fear memories. Yet, despite a strong clinical interest, a detailed understanding of these memory phases for contextual fear memories is still missing. Besides the well-known role of the hippocampus in en...

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ژورنال

عنوان ژورنال: Frontiers in Computational Neuroscience

سال: 2012

ISSN: 1662-5188

DOI: 10.3389/conf.fncom.2012.55.00158